Question | Answer |
1. Are visible cell and tissue changes unique to radiation exposure? | No, many types of trauma will produce similar or the same changes.
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2. With acute effects, are cell changes reversible? | Cell changes may or may not be reversible dependent upon dose and the proliferative capacity of the target
| 3. Are chronic effects reversible? | Chronic effects are due to irreversible damage and subsequent progressive changes or depletion or critical non-parenchymal cells such as blood vessels or stroma
| 4. What are the two types of healing? | regeneration and repair
| 5. What is regeneration? | damaged cells are replaced by the same functional cell type that was present before the irradiation occurred
| 6. What is repair? | the damaged cells are replaced by a different cell type which is non functional
| 7. What are the clinical factors affecting the response of tissue to radiation? | size of the dose, volume of tissue irradiated, and fractionation.
| 8. True or false. The hemopoietic system includes lymph nodes, circulating blood, bone marrow, and radiosensitive stem cells. | True
| 9. An ambient response occurs (with/without) exposure to radiation? | without
| 10. What portion(s) of the spinal cord is the most radiosensitive? | cervical & thoracic
| 11. What dose in Gy produces permanent sterility in males and females? | 5Gy
| 12. Genetic effects exhibit what kind of response? | linear, dose, and dose rate dependent response
| 13. True of false. Hair follicles are radioresistant. | false
| 14. True or false. Most circulating blood cells are radiosensitive? | false
| 15. True or false. Current theory supports the use of linear nonthreshold curves for diagnostic x-ray. | True
| 16. What is the most sensitive stage of the male sperm cell development? | spermatogonia
| 17. What is the most radiosensitive stage of the female ovum development? | mature follicle
| 18. What are the most radiosensitive mature blood cell type? | Lymphocytes
| 19. What are the most radioresistant mature blood cell type? | Erythrocytes
| 20. What are some examples of acute and chronic organ changes? | acute: inflammation, edema; Chronic: obstruction |