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QR Challenge: Radiation Biology Unit 7

QuestionAnswer
1. Are visible cell and tissue changes unique to radiation exposure?No, many types of trauma will produce similar or the same changes.
2. With acute effects, are cell changes reversible?Cell changes may or may not be reversible dependent upon dose and the proliferative capacity of the target
3. Are chronic effects reversible?Chronic effects are due to irreversible damage and subsequent progressive changes or depletion or critical non-parenchymal cells such as blood vessels or stroma
4. What are the two types of healing?regeneration and repair
5. What is regeneration?damaged cells are replaced by the same functional cell type that was present before the irradiation occurred
6. What is repair?the damaged cells are replaced by a different cell type which is non functional
7. What are the clinical factors affecting the response of tissue to radiation?size of the dose, volume of tissue irradiated, and fractionation.
8. True or false. The hemopoietic system includes lymph nodes, circulating blood, bone marrow, and radiosensitive stem cells.True
9. An ambient response occurs (with/without) exposure to radiation?without
10. What portion(s) of the spinal cord is the most radiosensitive?cervical & thoracic
11. What dose in Gy produces permanent sterility in males and females?5Gy
12. Genetic effects exhibit what kind of response?linear, dose, and dose rate dependent response
13. True of false. Hair follicles are radioresistant.false
14. True or false. Most circulating blood cells are radiosensitive?false
15. True or false. Current theory supports the use of linear nonthreshold curves for diagnostic x-ray.True
16. What is the most sensitive stage of the male sperm cell development?spermatogonia
17. What is the most radiosensitive stage of the female ovum development?mature follicle
18. What are the most radiosensitive mature blood cell type?Lymphocytes
19. What are the most radioresistant mature blood cell type?Erythrocytes
20. What are some examples of acute and chronic organ changes?acute: inflammation, edema; Chronic: obstruction

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