"Gout": HTML5 Crossword

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1. How long should urate-lowering therapy be continued in a patient with gout? (8)
3. The name for gout affecting the great toe (7)
6. Monosodium urate crystals are _______ birefringent (10)
8. Calcium pyrophosphate crystals are ______ birefringent (10)
10. Product of purine metabolism (8)
11. Shape of crystals seen in the synovial fluid of a patient with gout (6)
12. What is the classic type of effusion seen in elderly women with Milwaukee shoulder? (11)
13. Name of IV medication that can be used for refractory tophaceous gout (11)
15. The name for hard deposits of uric acid crystals in joints and tissues (5)
16. What medication should not be stopped in an acute gout flare? (11,0)

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2. The main indication to change to this medication is if the patient experiences allopurinol hypersensitivity syndrome (10)
4. _______ mg/dL or less is the goal uric acid level in the chronic treatment of gout with tophi (4)
5. What genetic disorder is associated with pseudogout? (15)
7. Use of what substance can precipitate a gout flare? (7)
9. What medication should be started within the first 72 hours (48 hours ideally) of a gout flare in order for it to work? (10)
14. Most common cause of inflammatory arthritis in men over age 40 (4)